Issue 10
May. 2023
Turn off MathJax
Article Contents
JOURNAL OF MECHANICAL ENGINEERING  > 2023  >  44(10): 353-361.
ZHOU Ting, WU Xueli, LI Xingjie, et al. Comparison of Antioxidant Activities of Three Kinds of Juices and Their Protective Effects on Oxidative Damage of Colon Cell NCM460[J]. Science and Technology of Food Industry, 2023, 44(10): 353−361. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022070108
Citation: ZHOU Ting, WU Xueli, LI Xingjie, et al. Comparison of Antioxidant Activities of Three Kinds of Juices and Their Protective Effects on Oxidative Damage of Colon Cell NCM460[J]. Science and Technology of Food Industry, 2023, 44(10): 353−361. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022070108
shu

Comparison of Antioxidant Activities of Three Kinds of Juices and Their Protective Effects on Oxidative Damage of Colon Cell NCM460

doi: 10.13386/j.issn1002-0306.2022070108
  • 1.

    West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China

  • 2.

    Sichuan Institute of Product Quality Supervision and Inspection, Chengdu 610100, China

  • Received Date: 13 Jul 2022
  • Issue Publish Date: 15 May 2023
    Abstract
  • To compare the contents of active ingredients and antioxidant activity of Rosa roxburghii Tratt juice (RRTJ), pomegranate juice (PJ) and blueberry juice (BJ) and investigate the protective effects of three kinds of fruit juices against dextran sulfate sodium (DSS)-induced oxidative damage in human normal colonic epithelial cells NCM460. There were 28 bioactive components in the three juices. The total polyphenols and total flavonoids of RRTJ were significantly higher than those in the PJ and BJ (P<0.05), 22.77 and 12.04 mg/mL, respectively. Meanwhile, the ABTS+· and DPPH· scavenging abilities of the juice were significantly higher than those in the PJ and BJ (P<0.05), and the half scavenging rate (IC50) was 4.00±0.32 and 10.03±0.51 μL/mL, respectively. Pearson correlation analysis indicated that the total polyphenol content of the juice was positively correlated with the ABTS+· scavenging ability (P<0.05). In addition, RRTJ had the strongest ability to alleviate DSS-induced oxidative damage in NCM460 cells, and 2 μL/mL RRTJ could restore the viability of oxidatively damaged NCM460 cells to a level comparable to the control and reduce the level of reactive oxygen species (ROS) in DSS-induced cells. The results showed that the content of total polyphenols in fruit juice was positively correlated with antioxidant capacity. The content of total polyphenols in juice was positively correlated with antioxidant capacity, and the antioxidant activity and the ability to alleviate DSS-induced oxidative damage in NCM460 cells were the strongest in vitro, which had the potential for in-depth research and development.

     

    • FullText(HTML)
  • loading
    • References(41)
  • [1]
    LIU P, LI Y, WANG R, et al. Oxidative stress and antioxidant nanotherapeutic approaches for inflammatory bowel disease[J]. Biomedicines,2021,10(1):85. doi: 10.3390/biomedicines10010085
    [2]
    LIGUORI I, RUSSO G, CURCIO F, et al. Oxidative stress, aging, and diseases[J]. Clinical Interventions in Aging,2018,13:757−772. doi: 10.2147/CIA.S158513
    [3]
    SIES H, JONES D P. Reactive oxygen species (ROS) as pleiotropic physiological signalling agents[J]. Nature Reviews Molecular Cell Biology,2020,21(7):363−383. doi: 10.1038/s41580-020-0230-3
    [4]
    ALATAB S, SEPANLOU S G, IKUTA K, et al. The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: A systematic analysis for the global burden of disease study 2017[J]. The Lancet Gastroenterology & Hepatology,2020,5(1):17−30.
    [5]
    GEICU O I, STANCA L, VOICU S N, et al. Dietary AGEs involvement in colonic inflammation and cancer: Insights from an in vitro enterocyte model[J]. Scientific Reports,2020,10(1):2754. doi: 10.1038/s41598-020-59623-x
    [6]
    RUDRAPAL M, KHAIRNAR S J, KHAN J, et al. Dietary polyphenols and their role in oxidative stress-induced human diseases: Insights into protective effects, antioxidant potentials and mechanism(s) of action[J]. Front Pharmacol,2022,13:806470. doi: 10.3389/fphar.2022.806470
    [7]
    ZHOU G, CHEN L, SUN Q, et al. Maqui berry exhibited therapeutic effects against DSS-induced ulcerative colitis in C57BL/6 mice[J]. Food Function,2019,10(10):6655−6665. doi: 10.1039/C9FO00663J
    [8]
    PACHECO M T, VEZZA T, DIEZ-ECHAVE P, et al. Anti-inflammatory bowel effect of industrial orange by-products in DSS-treated mice[J]. Food Function,2018,9(9):4888−4896. doi: 10.1039/C8FO01060A
    [9]
    VALKO M, LEIBFRITZ D, MONCOL J, et al. Free radicals and antioxidants in normal physiological functions and human disease[J]. International Journal of Biochemistry & Cell Biology,2007,39(1):44−84.
    [10]
    EBRAHIMI P, LANTE A. Polyphenols: A comprehensive review of their nutritional properties[J]. The Open Biotechnology Journal,2021,15(1):164−172. doi: 10.2174/1874070702115010164
    [11]
    DIREITO R, ROCHA J, SEPODES B, et al. Phenolic compounds impact on rheumatoid arthritis, inflammatory bowel disease and microbiota modulation[J]. Pharmaceutics,2021,13(2):145. doi: 10.3390/pharmaceutics13020145
    [12]
    XU J, VIDYARTHI S K, BAI W, et al. Nutritional constituents, health benefits and processing of Rosa roxburghii: A review[J]. Journal of Functional Foods,2019:60.
    [13]
    GIMÉNEZ-BASTIDA J A, ÁVILA-GÁLVEZ M Á, ESPÍN J C, et al. Evidence for health properties of pomegranate juices and extracts beyond nutrition: A critical systematic review of human studies[J]. Trends in Food Science & Technology,2021,114:410−423.
    [14]
    EL NEWEHY N M, ABD-ALHASEEB M M, OMRAN G A, et al. Comparative metabolomics reveal intraspecies variability in bioactive compounds of different cultivars of pomegranate fruit (Punica granatum L.) and their waste by-products[J]. Journal of the Science of Food and Agriculture,2022,102(13):5891−5902. doi: 10.1002/jsfa.11940
    [15]
    HE J Y, ZHANG Y H, MA N, et al. Comparative analysis of multiple ingredients in Rosa roxburghii and R. sterilis fruits and their antioxidant activities[J]. Journal of Functional Foods,2016,27:29−41. doi: 10.1016/j.jff.2016.08.058
    [16]
    LI H, FANG W, WANG Z, et al. Physicochemical, biological properties, and flavour profile of Rosa roxburghii Tratt, Pyracantha fortuneana, and Rosa laevigata Michx fruits: A comprehensive review[J]. Food Chemistry,2022,366:130509. doi: 10.1016/j.foodchem.2021.130509
    [17]
    赵斯尘, 王永刚. 药食同源刺梨的研究进展[J]. 食品工业,2022,43(3):186−191. [ZHAO S C, WANG Y G. Research progress of edible Rosa roxburghii Tratt[J]. The Food Industry,2022,43(3):186−191.
    [18]
    MATHON C, CHATER J M, GREEN A, et al. Quantification of punicalagins in commercial preparations and pomegranate cultivars, by liquid chromatography-mass spectrometry[J]. Journal of the Science of Food and Agriculture,2019,99(8):4036−4042. doi: 10.1002/jsfa.9631
    [19]
    MANDAL A, BHATIA D, BISHAYEE A. Anti-inflammatory mechanism involved in pomegranate-mediated prevention of breast cancer: The role of NF-kappa B and Nrf2 signaling pathways[J]. Nutrients,2017,9(5):436. doi: 10.3390/nu9050436
    [20]
    PEREZ R, LACA A, LACA A, et al. Environmental behaviour of blueberry production at small-scale in Northern Spain and improvement opportunities[J]. Journal of Cleaner Production,2022:339.
    [21]
    ZHOU L, XIE M H, YANG F, et al. Antioxidant activity of high purity blueberry anthocyanins and the effects on human intestinal microbiota[J]. LWT-Food Science and Technology,2020:117.
    [22]
    QNEIBI M, HANANIA M, JARADAT N, et al. Inula viscosa (L.) Greuter, phytochemical composition, antioxidant, total phenolic content, total flavonoids content and neuroprotective effects[J]. European Journal of Integrative Medicine,2021:42.
    [23]
    刘翰飞. 刺梨抗氧化抑菌作用的谱效关系研究 [D]. 贵阳: 贵州大学, 2020.

    LIU H F. Study on the spectrum-effect relationship of anti-oxidation and bacteriostasis of Rose roxburghii [D]. Guiyang: Guizhou University, 2020.
    [24]
    HE J M, YIN T P, CHEN Y, et al. Phenolic compounds and antioxidant activities of edible flowers of Pyrus pashia[J]. Journal of Functional Foods,2015,17:371−379. doi: 10.1016/j.jff.2015.05.045
    [25]
    CHEN G, KAN J. Characterization of a novel polysaccharide isolated from Rosa roxburghii Tratt fruit and assessment of its antioxidant in vitro and in vivo [J]. International Journal of Biological Macromolecules, 2018, 107(Pt A): 166-174.
    [26]
    DING A, WEN X. Dandelion root extract protects NCM460 colonic cells and relieves experimental mouse colitis[J]. Journal of Natural Medicines,2018,72(4):857−866. doi: 10.1007/s11418-018-1217-7
    [27]
    BHATTACHARYYA S, DUDEJA P K, TOBACMAN J K. ROS, Hsp27, and IKKbeta mediate dextran sodium sulfate (DSS) activation of IkappaBa, NFkappaB, and IL-8[J]. Inflammatory Bowel Diseases,2009,15(5):673−683. doi: 10.1002/ibd.20821
    [28]
    熊颖, 禹霖, 柏文富, 等. 不同品种蓝莓果实品质特征和抗氧化能力及多酚组成的比较[J]. 中南林业科技大学学报,2022,42(2):119−128. [XIONG Y, YU L, BAI W F, et al. Evaluation of quality characteristics, antioxidant ability and polyphenol composition of different blueberry cultivars[J]. Journal of Central South University of Forestry & Technology,2022,42(2):119−128.
    [29]
    BRIGHENTI V, GROOTHUIS S F, PRENCIPE F P, et al. Metabolite fingerprinting of Punica granatum L. (pomegranate) polyphenols by means of high-performance liquid chromatography with diode array and electrospray ionization-mass spectrometry detection[J]. Journal of Chromatography A,2017,1480:20−31. doi: 10.1016/j.chroma.2016.12.017
    [30]
    BECKER PERTUZATTI P, TEIXEIRA BARCIA M, GOMEZ-ALONSO S, et al. Phenolics profiling by HPLC-DAD-ESI-MS(n) aided by principal component analysis to classify Rabbiteye and Highbush blueberries[J]. Food Chemistry,2021,340:127958. doi: 10.1016/j.foodchem.2020.127958
    [31]
    WANG L T, LV M J, AN J Y, et al. Botanical characteristics, phytochemistry and related biological activities of Rosa roxburghii Tratt fruit, and its potential use in functional foods: A review[J]. Food Function,2021,12(4):1432−1451. doi: 10.1039/D0FO02603D
    [32]
    YANG Q Q, ZHANG D, FARHA A K, et al. Phytochemicals, essential oils, and bioactivities of an underutilized wild fruit Cili (Rosa roxburghii)[J]. Industrial Crops and Products,2020,143:11928.
    [33]
    CHIU H F, VENKATAKRISHNAN K, GOLOVINSKAIA O, et al. Gastroprotective effects of polyphenols against various gastro-intestinal disorders: A mini-review with special focus on clinical evidence[J]. Molecules,2021,26(7):2090. doi: 10.3390/molecules26072090
    [34]
    PISOSCHI A M, POP A. The role of antioxidants in the chemistry of oxidative stress: A review[J]. European Journal of Medicinal Chemistry,2015,97:55−74. doi: 10.1016/j.ejmech.2015.04.040
    [35]
    LIU C, CHAN L P, LIANG C H. The anti-aging activities against oxidative damages of Rosa roxburghii and multi-fruit concentrate drink[J]. Journal of Food and Nutrition Research,2020,7(12):845−850. doi: 10.12691/jfnr-7-12-5
    [36]
    TOPALOVIC A, KNEZEVIC M, IVANOVIC L, et al. Phytochemical screening of wild pomegranate (Punica granatum L.) juices from the market[J]. Journal of Food Composition and Analysis,2021:100.
    [37]
    YANG W J, GUO Y X, LIU M, et al. Structure and function of blueberry anthocyanins: A review of recent advances[J]. Journal of Functional Foods,2022:88.
    [38]
    FELGUS-LAVEFVE L, HOWARD L, ADAMS S H, et al. The effects of blueberry phytochemicals on cell models of inflammation and oxidative stress[J]. Advances In Nutrition,2022,13(4):1279−1309. doi: 10.1093/advances/nmab137
    [39]
    ALI H, JAHAN A, SAMRANA S, et al. Hepatoprotective potential of pomegranate in curbing the incidence of acute liver injury by alleviating oxidative stress and inflammatory response[J]. Frontiers in Pharmacology,2021,12:694607. doi: 10.3389/fphar.2021.694607
    [40]
    POUNIS G, COSTANZO S, BONACCIO M, et al. Reduced mortality risk by a polyphenol-rich diet: An analysis from the Moli-sani study[J]. Nutrition,2018,48:87−95. doi: 10.1016/j.nut.2017.11.012
    [41]
    卢薇, 费建军, 沈晓梅, 等. 五种果汁的酚类组成及其抗氧化、抗肿瘤细胞增殖活性研究[J]. 食品工业科技,2021,43:365−371. [LU W, FEI J J, CHEN X M, et al. Phenolic profiles, antioxidant and antiproliferative activities towards tumor cells of five fruit juices[J]. Science and Technology of Food Industry,2021,43:365−371. doi: 10.13386/j.issn1002-0306.2021070043
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    Figures(6)  / Tables(4)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views(20) PDF downloads(0) Cited by()
    Proportional views
    Related

    Copyright © 2009《 石油钻探技术 》 All Rights Reserved.

    Address：North-Star Times Tower, No.8 Beichendong Road, Chaoyang District, Beijing, China China Pos：100101

    Tel：010-84988317，84988356，84988357 Fax：021-64253812 Email：syzt@vip.163.com

    Beijing public network security equipment 11010502036328　Beijing ICP backup 17033152

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return