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JOURNAL OF MECHANICAL ENGINEERING  > 2022  >  38(5): 491-495.
Wang YX,Chen JJ,Cen Y,et al.Research advances on exosomes derived from adipose-derived mesenchymal stem cells in promoting diabetic wound healing[J].Chin J Burns Wounds,2022,38(5):491-495.DOI: 10.3760/cma.j.cn501120- 20210218-00057.
Citation: Wang YX,Chen JJ,Cen Y,et al.Research advances on exosomes derived from adipose-derived mesenchymal stem cells in promoting diabetic wound healing[J].Chin J Burns Wounds,2022,38(5):491-495.DOI: 10.3760/cma.j.cn501120- 20210218-00057.
shu

Research advances on exosomes derived from adipose-derived mesenchymal stem cells in promoting diabetic wound healing

doi: 10.3760/cma.j.cn501120-20210218-00057

  • Department of Burns and Plastic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China

Funds:

General Program of National Natural Science Foundation of China 81871574

Science and Technology Program of Sichuan Province of China 2020YFS0267

Scientific Research Project of Health Commission of Sichuan Province of China 19PJ097

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  • Corresponding author: Zhang Zhenyu, Email: zzy137731@163.com
  • Received Date: 18 Feb 2021
    Available Online: 20 Jul 2022
  • Issue Publish Date: 20 May 2022
    Abstract
  • Impaired healing of diabetic wounds is mainly attributed to its pathological mechanism, and refractory diabetic wounds bring heavy burdens to patients and society. Exosomes derived from stem cells possess the similar ability as stem cells in promoting tissue regeneration and more clinical advantages and are gradually playing important roles in wound healing. In recent years, researches have shown that exosomes derived from adipose-derived mesenchymal stem cells (ADSC-EXOs) can promote the healing of diabetic wounds by participating in various processes of wound healing. This article reviews the pathological mechanism leading to impaired healing of diabetic wounds, the related mechanism and the application prospect of ADSC-EXOs in promoting diabetic wound healing.

     

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    • References(45)
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