Advances on the research and treatment of autoimmune disease-related chronic wounds
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摘要: 自身免疫病是由于机体免疫系统被错误导向进而攻击宿主自身所引发的一种疾病。该类疾病患者全身状况差,受血管和皮肤组织病变以及治疗药物等的影响,皮肤一旦破溃极易形成迁延不愈的慢性创面,该类创面治疗难度较大,需要多学科医师联合诊疗。基于此,该文对自身免疫病相关慢性创面的研究和治疗进展进行综述,以期为其临床治疗提供参考。Abstract: Autoimmune disease is a disease caused by the body's immune system being misdirected to attack the host itself. Patients with this type of diseases are in poor general condition, and are affected by vascular and skin tissue lesions, and therapeutic drugs. Once the skin is broken, chronic wounds that do not heal could easily develop. This type of wounds is difficult to treat and requires joint diagnosis and treatment of multidisciplinary physicians. Therefore, this article reviews the advances on research and treatment of autoimmune disease-related chronic wounds in order to provide reference for their clinical treatment.
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Key words:
- Autoimmune diseases /
- Stem cells /
- Extracellular vesicles /
- Chronic wound /
- microRNA /
- DNA nanotechnology
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